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Clarrio.ai

Therapeutic area · Healthy aging and prevention

Longitudinal longevity tracking beyond periodic assessments

Longevity programs are judged on change over months. Clarrio.ai turns assessments, biomarkers and everyday data into one longitudinal record for members, clinicians and program leaders. Align clinical, treatment and behavioral information on one shared longitudinal timeline, where available and appropriate to the program.

What Clarrio.ai captures

  • Lifestyle and wellbeing check-ins
  • Protocol adherence
  • Nutrition logs
  • Lab biomarkers
  • Wearable sleep, HRV and activity
  • Body composition

Longitudinal health intelligence

Disease, treatment and behavior on one timeline

Align clinical observations, medication or intervention history, and daily-life context without losing source meaning. Available data and review boundaries depend on the program.

One person / one shared timeline

Illustrative research data · Synthetic demonstration

Health and disease trajectories

Resting heart rate

Treatments and interventions

Exposure · dose · reported experience

12345678

Behavior and daily life

Average sleep

Shared time axis / weeks

Week 4 / Disease64 bpm · Connected observation

Week 4 / TreatmentPlan adjustment · Recovery days added

Week 4 / Behavior7.1 h · Routine resumed

Open related use case

Separate measures and independently scaled channels; values appear in their own units. Temporal alignment does not establish causality.

The evidence gap

An annual assessment cannot show what changed in between

Longevity and preventive health clinics run comprehensive assessments: labs, body composition, cardiometabolic tests, fitness. Between those assessments, members wear devices and follow protocols, but that data rarely returns to the clinic in a usable form.

Without a continuous record, clinics struggle to show members their progress, to adjust protocols with evidence, or to report program outcomes to leadership and partners.

Cardiometabolic

Lipids, glucose and blood pressure measured a few times a year.

Sleep & recovery

Wearable data stays in consumer apps.

Function

Strength, VO2 max and mobility tested occasionally.

Wellbeing

Stress and mood are rarely tracked systematically.

The challenge

Annual labs miss the months that decide the result

A metabolic or healthy-aging program is judged on change over months, yet most of the evidence arrives as two or three lab draws a year. Training blocks, travel, illness and diet changes happen in between and leave no trace in the record. The result is a program that can report where a member ended up, but not what moved them there.

Toggle the chart to compare what a visit-based record shows with what the continuous record shows for the same synthetic patient.

Fasting glucose (mg/dL) over 120 days

Observations2

Events in periodNot visible

Events with no nearby visit3 of 3

Two lab draws suggest a stable member. The continuous record shows three distinct episodes, each with its own context, that the draws never saw.

Illustrative · synthetic data

Between draws

Response is invisible

Labs confirm a result; they rarely explain which protocol change produced it.

Per member

Averages hide responders

Program-level averages blend members who respond strongly with those who do not respond at all.

Renewal

Value is hard to show

Without a visible trajectory, members and leadership see cost, not progress.

How Clarrio.ai addresses the gap

Collection, integration and analytics, designed for this area

  1. 01

    Seven health domains

    Cardiometabolic, sleep, activity, biomarkers, lifestyle, wellbeing and environmental context.

  2. 02

    Member app

    Device connection, check-ins and personal progress views.

  3. 03

    Clinic dashboards

    Baseline versus follow-up, domain profiles and engagement.

  4. 04

    Research-ready data

    Program datasets for internal review or partnerships.

Data captured

Three layers of data, kept distinct

Select a layer. Exact sources depend on deployment configuration and data permissions.

Captured from patients or caregivers in the Patient App.

  • Lifestyle and wellbeing check-ins
  • Protocol adherence
  • Nutrition logs

Product workflow

How the record is built, step by step

Select a step to see what happens. Sources are captured through the Patient App and integrations, harmonized on the Platform and summarized by Intelligence.

Sources

  • Lab panels & biomarkers
  • CGM & wearables
  • Nutrition check-ins
  • Body composition

Clarrio.ai workflow

Outputs

  • Member response view
  • Pre-visit trajectory
  • Program analytics

Stakeholder outputs

Role-specific views of the longitudinal record

Each role receives a different view of the same longitudinal record. Values are synthetic.

Member

What Works for Me

Members see which routines coincided with better readings in their own data, framed as associations rather than advice.

Clarrio.ai / What Works for MeSynthetic
  • Consistent sleep windowStrongGlucose variability lower on weeks with regular sleep
  • Post-meal walkModerateLower 2-hour readings on 9 of 14 logged days
  • Late mealsWeakPattern unclear; more data needed

Physician

Pre-visit summary

Before the review, the physician reads a dated summary of the period since the last draw instead of reconstructing it from memory.

Clarrio.ai / Pre-visit summarySynthetic
  • Glucose trend↓ since Day 55Follows reported diet change
  • Illness episodeDay 92Temporary rise; resolved within 10 days
  • Data completeness86%Wearable gaps during travel

Clinic lead

Program analytics

Leadership sees engagement and trajectory across the member base, the basis for program reporting.

Clarrio.ai / Program analyticsSynthetic
  • Active members1,240Synced in last 14 days
  • Improving trajectories38%Share with downward glucose trend
  • At risk of disengaging96No check-in in 21 days

Worked examples

Two illustrative scenarios

Member, metabolic program

A plateau explained

  1. Week 0

    Baseline panel; protocol set.

  2. Weeks 2–6

    CGM shows evening spikes after late training sessions.

  3. Week 7

    Coach sees the pattern in the pre-call summary and moves training earlier.

  4. Week 16

    Second panel; the record shows when the change began.

Illustrative · synthetic data

Clinic leadership

Program reporting

  1. Month 1

    Cohort defined: members enrolled this quarter.

  2. Month 3

    Dashboard shows completeness and trajectories.

  3. Month 6

    Export supports an internal program review.

Illustrative · synthetic data

FAQ

Longevity & preventive health questions

Research & operational outputs

Research and operational deliverables

Member longitudinal dashboard

All domains on one timeline.

Health domain profiles

Where each member stands, and how it is moving.

Baseline vs follow-up

Structured comparison between assessments.

Program analytics

Engagement and trajectories across the member base.

Value for each stakeholder

Longevity clinics

Evidence of member progress and program value.

Physicians & coaches

Between-assessment context for protocol decisions.

Members

A visible, personal record of change.

Pharmaceutical & biotech

Research partnerships on healthy aging cohorts, with consent.

Program evaluation

Where Clarrio.ai can create measurable value

These are the KPIs we agree with customers before deployment, measured against their own baseline. Data coverage, patient experience and clinical outcomes answer different questions. Higher engagement alone does not demonstrate better health or lower utilization.

Explore benefits and evidence
LeverHow it is measured
Member retentionMembers renewing relative to eligible
EngagementMembers syncing data in last 14 days
Clinician timeMinutes spent compiling pre-review data
Program reportingHours to produce outcome reports

Illustrative use case

A year-long healthy-aging program

Longevity clinic, illustrative

A year-long healthy-aging program

  1. Month 0

    Baseline assessment and device connection.

  2. Months 1–6

    Weekly data sync; monthly wellbeing check-ins.

  3. Month 6

    Mid-point review with domain profiles.

  4. Month 12

    Follow-up assessment compared against baseline.

Illustrative · synthetic data

Cardiometabolic healthSleep and recoveryFunctional healthBiomarker tracking

Clarrio.ai has joined Mayo Clinic Platform's Solutions Studio, supporting its mission to advance interoperable, data-driven healthcare innovation. This does not imply endorsement or clinical validation.

  • Consent and data governance
  • Privacy-by-design principles
  • Role-based access
  • Flexible deployment
  • Data residency options
  • FHIR-based interoperability
  • Research-use positioning, not diagnosis

See Clarrio for Longevity Clinics

See Clarrio for Longevity Clinics

Evidence interpretation

Assessments are intermittent; everyday observations are selective

Keep laboratory intervals distinct from device sampling. A member-reported routine change can explain the review question without establishing its cause. Payer-facing evaluation needs a defined preventive service and outcomes beyond participation.

Benefits in practice

From longevity & preventive health observations to a useful review

Longevity clinics

Make the program review about the interval, not just the latest result

An annual assessment and a wearable dashboard answer different questions. The assessment describes a scheduled measurement; a device records selected aspects of everyday life. Neither alone explains whether a member could sustain a routine, why observations stopped or what they want to discuss. Combining them is useful only when the dates, measurement methods and member context remain distinguishable.

  1. 01

    Agree a review question

    Choose a specific interval and member goal rather than collecting every available signal.

  2. 02

    Build the dated record

    Use the Patient App for member context, the Platform for available source coverage and Intelligence for source-aware review.

  3. 03

    Prepare the conversation

    Compare like-for-like observation windows, inspect gaps and bring unresolved questions to the physician or coach.

For the professional team

Physicians and coaches gain a structured basis for preparation: which period changed, which source supports the observation and which question remains open. Leadership can separately review onboarding, connection support and review workload. A more detailed chart does not establish that the program improved health or extended life.

For patients, members and caregivers

Members can explain travel, routines and personal priorities alongside their observations. The benefit is continuity of the conversation, not another unexplained score. A useful member journey also makes room for people without a wearable and makes clear when the team will review what they share.

For payers and program funders

For an employer or payer considering a preventive program, participation and data coverage are starting points, not evidence of prevention or savings. Define the eligible population, program services and evaluation period before comparing results. A self-pay clinic membership does not imply an insurance coverage benefit.

Illustrative review brief
Review period
Assessment dates and available between-visit observations
Source context
Device type, lab units and member-reported routine changes
Unresolved question
What should the member and team discuss at the next review?

Workflow illustration · not a customer result or live record

What to evaluate before making a claim

Track whether intended records are available, whether reviews are completed and whether members find the reporting burden acceptable. Analyze renewals separately from health outcomes; neither should be attributed to a software workflow without a suitable evaluation.

Explore evidence and evaluation

Payers & health economics

Distinguish richer patient context from evidence of value

Claims and encounter datasets can describe recorded utilization without fully capturing function, experience or the practical burden of a program. Patient reports add a different perspective, but they can be incomplete or drawn from a population unlike the members covered by a payer. The task is to establish whether those observations are suitable for a specific appraisal question, not to turn engagement into a savings claim.

  1. 01

    Define the appraisal question

    Specify the relevant covered population, decision, comparator where needed and evaluation horizon.

  2. 02

    Assess data suitability

    Review provenance, participation, measurement windows and missingness before examining results.

  3. 03

    Build the evidence account

    Combine appropriately governed patient experience with relevant clinical or utilization evidence; document assumptions and limits for expert appraisal.

For the professional team

HEOR and population-health teams can examine how reported experience varies across the observation period and which groups are represented. A useful output explains the denominator behind a measure and the observations excluded from analysis. Governance must also define the permitted purpose of any linkage to payer-held data.

For patients, members and caregivers

The member perspective should remain visible in a program evaluation: burden, everyday function, access and what participants consider meaningful. Reporting should not become an unexplained condition of receiving services. Explain the collection purpose and permitted uses in a way members can understand.

For payers and program funders

Decision support means an inspectable evidence package, not an automatic reimbursement verdict. Include the target population, relevant baseline differences, data sources, follow-up and limitations. Cost and utilization conclusions need appropriate data and analysis; neither can be inferred from app activity or observation coverage.

Illustrative review brief
Decision context
Population, appraisal question and evaluation horizon
Suitability account
Provenance, completeness, accuracy and relevance
Interpretation boundary
What the analysis can support and what remains uncertain

Workflow illustration · not a customer result or live record

What to evaluate before making a claim

Separate program participation, patient-reported experience, clinical outcomes and economic endpoints. Define each before collection, use an appropriate comparison where the question requires one and examine whether findings transfer to the covered population.

Explore evidence and evaluation

Patients, members & caregivers

Give the person contributing data a meaningful place in the workflow

A person can complete many questions without understanding why they are being asked or who will read the answers. Device observations may look precise while missing personal context. A useful longitudinal journey starts with the person's priorities and makes the reporting purpose, burden and review arrangements understandable.

  1. 01

    Explain the purpose

    Agree what the care or research program needs to learn and what participation involves.

  2. 02

    Capture lived experience

    Use appropriate reports alongside available observations; distinguish the patient's own answers from caregiver observations.

  3. 03

    Bring context to review

    Discuss a dated interval with the responsible professional, including what is missing and what matters to the person.

For the professional team

Teams gain context for a more specific conversation, but should not assume that a missed report means a person disengaged. Accessibility, fatigue, language and connectivity may affect reporting. Define support and review arrangements before introducing new questions.

For patients, members and caregivers

Patients and members can keep a dated account of experiences they might otherwise forget. Caregivers can contribute observations when appropriately scoped, without replacing the person's own perspective. Personal patterns invite discussion; they are not instructions or proof that a particular routine produced an outcome.

For payers and program funders

A program's apparent reach can hide who could not participate. Payers and commissioners should examine access, reporting burden and representativeness alongside outcome evidence. Patient experience is an important perspective in appraisal, not a shortcut to an economic conclusion.

Illustrative review brief
Personal context
The person's own priorities and dated reports
Reporting perspective
Patient answer or appropriately identified caregiver observation
Review arrangement
Who reviews reports, when and through which contact pathway

Workflow illustration · not a customer result or live record

What to evaluate before making a claim

Ask whether reporting is understandable, manageable and meaningful. Examine completion alongside accessibility and support needs. A high completion rate alone does not show that people feel heard or that a program has improved their health.

Explore evidence and evaluation

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Explore disease, treatment and behavior together

Explore how clinical, treatment and behavioral information align around your program and the research or review questions your team needs to answer.

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